I get this occasionally , I have found that the following has solved this three times for me. Don't ask me why it has worked, it just works. Turn off laptop. Remove battery. Now press power button and keep it pressed for about 30 seconds. Now replace battery and plug in mains. Turn on computer, you should have your touchpad back working again.
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I know its an old thread but I still even in 2022 use my Dell e6410 everyday.
I get this occasionally , I have found that the following has solved this three times for me. Don't ask me why it has worked, it just works. Turn off laptop. Remove battery. Now press power button and keep it pressed for about 30 seconds. Now replace battery and plug in mains. Turn on computer, you should have your touchpad back working again.